Insulin in Kenya: all you need to know about insulin

Insulin Kenya

Insulin is a hormone made by the pancreas that allows your body to use sugar (glucose) from carbohydrates in the food that you eat for energy or to store glucose for future use. Insulin helps keeps your blood sugar level from getting too high (hyperglycemia) or too low (hypoglycemia). Insulin Kenya
The hormone insulin is a main regulator of the glucose (sugar) levels in the blood. Insulin is produced in the pancreas. To be more specific, it’s produced by the beta cells in the islets of Langerhans in the pancreas. When we eat, glucose levels rise, and insulin is released into the bloodstream.

Insulin Injection (Insulin medication)
Insulin is used to treat a number of diseases including diabetes and its acute complications such as diabetic ketoacidosis and hyperosmolar hyperglycemic states.It is also used along with glucose to treat high blood potassium levels.  ( Read on Endocrinologists in Kenya)

Types of insulin
1.Fast-acting : Includes the insulin analogues aspart, lispro, and glulisine. These begin to work within 5 to 15 minutes and are active for 3 to 4 hours.
2.Short-acting: Includes regular insulin which begins working within 30 minutes and is active about 5 to 8 hours.
3.Intermediate-acting: Includes NPH insulin which begins working in 1 to 3 hours and is active 16 to 24 hours
4.Long-acting: Includes the analogues glargine and detemir, each of which begins working within 1 to 2 hours and continue to be active, without major peaks or dips, for about 24 hours, although this varies in many individuals.
5.Ultra-long acting: Currently only includes the analogue degludec, which begins working within 30–90 minutes, and continues to be active for greater than 24 hours
6.Combination insulin products (Pre-mixed): Includes a combination of either fast-acting or short-acting insulin with a longer acting insulin, typically an NPH insulin. The combination products begin to work with the shorter acting insulin (5–15 minutes for fast-acting, and 30 minutes for short acting), and remain active for 16 to 24 hours.

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Insulin medication dosage
Your provider(doctor) will prescribe an insulin dose regimen for you.
If you take insulin, you will either be on a fixed insulin dose therapy, whereby your insulin doses stay the same each day, or a flexible dose therapy, whereby you have freedom to change your doses.
One international unit of insulin (1 IU) is defined as the “biological equivalent” of 34.7 μg pure crystalline insulin

Insulin medication effect on exercise
During exercise, your body burns glycogen, a form of glucose that is stored in your muscles. After exercise, your muscles replenish their glycogen stores with glucose from the bloodstream. The more glycogen that is burned during a bout of activity, the longer the body’s insulin sensitivity is improved.
Low- to moderate-intensity exercise generally leads to a reduction in blood glucose levels resulting from increased glucose uptake by active muscles. … The acute improvements in glucose tolerance and insulin sensitivity after exercise can last from 24 to 72 hours
Insulin pumps in Kenya

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Insulin Pumps Kenya

Insulin pumps are portable devices attached to the body that continuously deliver amounts of rapid or short acting insulin via a catheter placed under the skin.
Because the insulin pump stays connected to the body, it allows the wearer to modify the amount of insulin they take within the press of a few buttons at any time of the day or to program in a higher or lower rate of insulin delivery to occur at a chosen time, which can be when sleeping.
An insulin pump consists of the main pump unit which holds an insulin reservoir which typically holds between 176 and 300 units of insulin.
The reservoir is attached to a long, thin piece of tubing with a needle or cannula at one end.
The tubing and the bit at the end are called the infusion set. Insulin pump therapy is also referred to as continuous subcutaneous insulin infusion therapy.
insulin syringes

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insulin syringes

An insulin syringe has three parts: a needle, a barrel, and a plunger.

  • The needle is short and thin and covered with a fine layer of silicone to allow it to pass through the skin easily and lessen pain. A cap covers and protects the needle before it is used.
  • The barrel is the long, thin chamber that holds the insulin. The barrel is marked with lines to measure the number of insulin units.
  • The plunger is a long, thin rod that fits snugly inside the barrel of the syringe. It easily slides up and down to either draw the insulin into the barrel or push the insulin out of the barrel through the needle. The plunger has a rubber seal at the lower end to prevent leakage. The rubber seal is matched with the line on the barrel to measure the correct amount of insulin.

Insulin resistance
Insulin resistance is a pathological condition in which cells fail to respond normally to the hormone insulin. The body produces insulin when glucose starts to be released into the bloodstream from the digestion of carbohydrates (primarily) in the diet. Under normal conditions of insulin reactivity, this insulin response triggers glucose being taken into body cells, to be used for energy, and inhibits the body from using fat for energy, thereby causing the concentration of glucose in the blood to decrease as a result, staying within the normal range even when a large amount of carbohydrates is consumed. During insulin resistance, however, excess glucose is not sufficiently absorbed by cells even in the presence of insulin, thereby causing an increase in the level of blood sugar.
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Insulin prices in Kenya

NB:

We dont stock,sell or endorse any of the products listed.The prices are just averages,may change with time.and this list is only for educational purposes:

A:
Highly Purified Human Insulin
1.Insulin Lispro

    • Actrapid® (Novo-Nordisk) injection 100i.u/ml (10ml) Ksh: 550
    • Actrapid® (Novo-Nordisk) Penfill 100i.u/ml ,3ml (5’s) Ksh: 4300
    • Humalog® (Eli lilly) 100 i.u/ml) cartridge 3ml X 5’s Ksh: 6200

Vials 100i.u/ml (10ml) Ksh:3100

  • Humulin R® (Eli Lilly) Regular 100 i.u/ml
    10ml vial = Ksh : 1950
    4ml vial = Ksh: 700
    cartridge 3ml X 5’s = Ksh : 4500
  • Humulin N® (Eli Lilly) NPH Insulin 100i.u
    10ml vial= 1950
    cartridge 3ml X 5’s = Ksh : 4500
  • Humulin Regular® (Eli Lilly) Cartridge Soluble/Neutral
    3ml X 5’s = 3600
  • Insuget Regular® (Getz)
    100i.u 10ml = Ksh: 1000
  • Insulin 30/70® (M.J.Biopharm)
    30% soluble insulin /70% isophane-human rDNA insulin 100i.u 10ml= 1900
    Cartridge 3ml X 5’s = Ksh :4500
  • Wosulin 30/70® (Wockhardt)
    100i.u 10ml = Ksh: 550
  • Insulin 30/70® (M.J.Biopharm)
    30% soluble insulin /70% isophane-human rDNA insulin 100i.u 10ml= 600
  • Wosulin N® (Wockhardt) NPH Insulin 100i.u
    10ml vial= 800
  • Wosulin R® (Wockhardt) Regular 100i.u 10ml vial = Ksh: 800

2.Insulin Aspart

  • NovoRapid® (Novo-Nordisk) injection 100i.u/ml 10ml= Ksh: 3900
  • NovoRapid Flexpen® (Novo-Nordisk)inj,..100i.u /ml 3ml × 5’s = Ksh:8600

3.Isulin Glargine

  • Lantus® (Sanofi Aventis)
    10ml = Ksh: 4100
  • Lantus Solostar® (Sanofi Aventis)
    3ml Cartridge x 5 disposable pens,,5’s =Ksh: 8900

B:
Biphasic/ Intermediate acting Insulins

  • Insuget® (Getz) soluble 30%/70% NPH inj 100i.u/ml 10ml= Ksh:100
  • inj Isophane NPH 10ml =1600
  • Insulatard® (Novo-Nordisk) NPH inj, 100i.u/ml 10ml =Ksh: 550
    penfill 100i.u/ml 3mlx5’s = Ksh: 4300
  • Mixtard 30® (Novo-Nordisk) soluble 30%/70% NPH inj 100i.u/ml 3ml x 5’s =Ksh 4300
    10ml =Ksh: 550
  • Novomix 30® (Novo-Nordisk) insulin aspart 30% + protaminated aspart 70% inj, 100i.u/ml
    3ml x 5’s =Ksh: 6800

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References for Insulin Kenya

  • Chiu HK, Tsai EC, Juneja R, et al. (August 2007). “Equivalent insulin resistance”. Diabetes Research and Clinical Practice. 77 (2): 237–44.
  • Brown, Dave D (2003). USMLE Step 1 Secrets. p. 63.
  • Mahoney BA, Smith WA, Lo DS, Tsoi K, Tonelli M, Clase CM (April 2005). “Emergency interventions for hyperkalaemia”. The Cochrane Database of Systematic Reviews (2): CD003235
  • Kalra S, Kalra B, Agrawal N (2010). “Oral insulin”. Diabetology & Metabolic Syndrome.

Insulin Kenya

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